COMPREHENSIVE ANALYSIS OF THE TRANSCRIPTOME-WIDE M6A METHYLATION IN MOUSE PACHYTENE SPERMATOCYTES AND ROUND SPERMATIDS

Comprehensive Analysis of the Transcriptome-Wide m6A Methylation in Mouse Pachytene Spermatocytes and Round Spermatids

Spermatogenesis, an efficient and complex system in male germline development, requires a series of elaborately regulated genetic events in which diploid spermatogonia differentiate into haploid spermatozoa.N6-methyladenosine (m6A) is an important epigenetic RNA modification that occurs during spermatogenesis.ALKBH5 is an m6A eraser and knocking ou

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Multifactor models in the analysis of mutual fund effectiveness

The aim of this paper is to examine the efficiency of Polish mutual funds.The applied performance measures are parameters of the models developed by Jensen, Internal Round Cap Fama-French and Carhart.By means of average returns, it is found that equity funds are not able to outperform the benchmark in a statistically significant manner and use prem

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Remaining Useful Life for Heavy-Duty Railway Cast Steel Knuckles Based on Crack Growth Behavior with Hypothetical Distributions

Abstract The current research on the integrity of critical structures of rail vehicles mainly focuses on the design stage, which needs an effective method for assessing the service state.This paper proposes a framework for predicting the remaining useful life (RUL) of in-service structures with and without visible cracks.The hypothetical distributi

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Multiscale Applications of Two Online-Coupled Meteorology-Chemistry Models during Recent Field Campaigns in Australia, Part II: Comparison of WRF/Chem and WRF/Chem-ROMS and Impacts of Air-Sea Interactions and Boundary Conditions

Air-sea interactions play an important role in atmospheric circulation and boundary layer conditions through changing convection processes and surface heat fluxes, particularly in coastal areas.These changes can affect the concentrations, distributions, and lifetimes of atmospheric pollutants.In this Part II paper, the performance of the Weather Re

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